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Last, but not least! (Quoted from: Clinical Aviation Medicine; Rayman,R  2000)

The Breakoff Phenomenon

Rayman and Gillingham and Previc describe a rare event experienced by Pilots at very high altitudes who feel they have indeed “slipped the surly bonds on earth”.The term breakoff covers a variety of high altitude flight experiences, from simply feeling good through euphoria to psychological detachment. As noted by Rayman,it is important to advise pilots flying at high flying altitudes of the phenomenon and the need to report any such unusual experience. Psychiatric consultation should be requested if the event degrades flying performance or if the pilot is negativeley influenced by the experience after return to earth.